PRE-CLINICAL & CLINICAL STUDIES
PRE-CLINICAL STUDIES OF BriDGE BY THE REGENERATIVE MEDICAL CENTER AT OHIO STATE UNIVERSITY
Our BriDGE Collagen Technology & Products
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Our BriDGE Collagen Technology & Products have been extensively studied by leading researchers. One of our studies was conducted by the highly respected Regenerative Medicine Center at the Ohio State University.
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Their studies found that:
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BriDGE is stabilized intact collagen that degrades very slowly;
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BriDGE collagen matrix attracts, nourishes the patient’s own growth factors;
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BriDGE collagen matrix stimulates the patient’s own antimicrobial defenses.
BriDGE Before Implant
BriDGE 3 Days Post-Implant
Macrophages
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Keratinocytes
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New Tissue
BriDGE Collagen Matrix
Accelerates Healing … Prevents Infection
RIGHT AT THE WOUND SITE … 24/7
Another study, a 12-week sheep tendon implant, was conducted by the Surgery and Orthopedic Research Laboratory at the University of New South Wales on our BPMatrix product.
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BPMatrix is a collagen patch from our BriDGE collagen processing technology.
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The purpose of the study was to characterize the tissue regenerative properties of BPMatrix and compare it to the published results of another collagen implant, Regeneten.
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BPMatrix vs Regeneten® Collagen (S&N)
Implants in Sheep Shoulder
BPMatrix Implant at 6 weeks
B. Walsh, J Brunelle 2020
Regeneten Implant at 12 weeks
C. Van Kampen, S Arnoczky et al. 2013
Findings by independent lab:
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BPMatrix implant generated new tendon tissue twice as fast as Regeneten;
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No inflammatory response to BPMatrix implant;
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Slowly degrading BPMatrix implant still generating new tendon tissue.
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A CLINICAL STUDY FROM 2012
Conducted by Dr. J. Alexander & Dr. D. Yeager
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Found on an early version of our products that:
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For 34 patients with 37 diabetic foot wounds;
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Overall healing rate at 12 weeks was 75.7%;
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Median time to closure was 7.0 weeks;
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All but one wound was treated with a single application of our product.